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Přizpůsobit se rekrut Slepá víra overall mutation load and p53 mutations Jsou v depresi Dlouho kondenzátor

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Frequency of p53 mutations in human cancers. (A) Schematic picture... |  Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram

Gain-of-function p53 protein transferred via small extracellular vesicles  promotes conversion of fibroblasts to a cancer-associated phenotype -  ScienceDirect
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype - ScienceDirect

Germline TP53 mutations undergo copy number gain years prior to tumor  diagnosis | Nature Communications
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications

Biomolecules | Free Full-Text | p53's Extended Reach: The Mutant p53  Secretome
Biomolecules | Free Full-Text | p53's Extended Reach: The Mutant p53 Secretome

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Rare Mutation of TP53 Gene Leaves People at Higher Risk for Multiple  Cancers - Penn Medicine
Rare Mutation of TP53 Gene Leaves People at Higher Risk for Multiple Cancers - Penn Medicine

The p53 network: cellular and systemic DNA damage responses in cancer and  aging: Trends in Genetics
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

The p53 Protein: Mutations, Cancer & Cell Signalling - Assay Genie
The p53 Protein: Mutations, Cancer & Cell Signalling - Assay Genie

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell  Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia  | Haematologica
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway:  Cell
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway: Cell

TP53 mutation spectrum in primary colorectal cancers. a Proportion of... |  Download Scientific Diagram
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram

Pathogenesis of TP53-mutated Acute Myeloid leukemia | Laboratory of Daniel  C. Link, M.D. | Washington University in St. Louis
Pathogenesis of TP53-mutated Acute Myeloid leukemia | Laboratory of Daniel C. Link, M.D. | Washington University in St. Louis

Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune  escape through PHLPP2/AKT/PD-L1 pathway
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway

Development of TP53 mutations over the course of therapy for acute myeloid  leukemia - Alwash - 2021 - American Journal of Hematology - Wiley Online  Library
Development of TP53 mutations over the course of therapy for acute myeloid leukemia - Alwash - 2021 - American Journal of Hematology - Wiley Online Library

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?

Homogenous TP53mut-associated tumor biology across mutation and cancer  types revealed by transcriptome analysis | Cell Death Discovery
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery

Frontiers | A TP53-Associated Immune Prognostic Signature for the  Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive  Bladder Cancer
Frontiers | A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer

Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with  the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes

Omics analyses of a somatic Trp53R245W/+ breast cancer model identify  cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS

Gaining insights into relevance across cancers based on mutation features  of TP53 gene - ScienceDirect
Gaining insights into relevance across cancers based on mutation features of TP53 gene - ScienceDirect

Significance of TP53 mutation in bladder cancer disease progression and  drug selection [PeerJ]
Significance of TP53 mutation in bladder cancer disease progression and drug selection [PeerJ]

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?